Auditory neuroscientists at the University of Michigan Medical School started investigating hearing loss biochemistry in 1987, led by Josef M. Miller, Ph.D., the director of the Kresge Hearing Research Institute at the University of Michigan Medical School.
Basic research was continually supported by the National Institutes of Health. A landmark 2005 lab study demonstrated the ACEMg formula protected inner ear cells from oxidative stress-related noise damage up to 30dB, reducing noise-induced hearing loss by 75%. Read the peer-reviewed article.
Translational research started in 2007. The project moved to Amsterdam in 2012 after winning a medical innovation grant that resulted in the paper explaining exactly how Soundbites works, the Soundbites softgel product, and a decision to collect real-world clinical data instead of random control trial (RCT) data. Learn about ACEMg-to-Soundbites translational research.
Researchers overcame the clinical data obstacle with real-world evidence studies, starting with a one-night pilot study conducted on a ferryboat taking EDM fans to an overnight festival during the annual Amsterdam Dance Event. Watch the aftermovie.
The clinical data milestone was reached in 2024 at the conclusion of a 2-year real-world evidence clinical study that demonstrated Soundbites preserved or improved hearing for 75.3% of daily users, within most improvement happening within the first six months. Results continued with ongoing use. Read the report.
The 24-week OTIS public health study started enrolling in December, 2024 and is planned to continue for years, gathering Soundbites epidemiological data quantifying improvement in hearing sensitivity, tinnitus, and hyperacusis symptoms. All new Soundbites customers can also take the 24-week OTIS test.
“I have extreme sensitivity to normal sound levels. I could barely go into a store. Now I do my own errands. I'm getting a part of my life back that I thought was gone forever. I’ve been using Soundbites for two years and will take it for the rest of my life!”
“Tinnitus is permanent like tattoos, but the suffering doesn’t have to be. Soundbites is extremely effective. I use it every day to keep my tinnitus out of the way of my life.”
"I have found Soundbites to be of clear benefit for patients. These real changes are clinically important. The significance of this achievement cannot be overstated."
"After taking Soundbites for
over a year, my audiograph
showed a freeze in hearing
decline and improvement in frequencies which had
shown a decline."
Sensorineural hearing loss, or SNHL, is the medical term for hearing loss caused by damage and dysfunction of inner ear nerve cells. SNHL is commonly called hearing loss because it accounts for more than 90% of all hearing loss.
Ask someone with hearing loss to think back on how it happened and they'll likely tell you about loud music and live concerts, or noise from motorsports, various machines, manufacturing, military service or living in a noisy city.
Tinnitus is called ringing in the ear, and it's highly correlated with hearing loss.Temporary tinnitus is a warning sign and it goes away. When it's permanent it's an incurable neurological disorder indicating hearing system dysfunction.
Soundbites helps preserve cognitive health and reduces dementia risk because hearing loss is known to hasten cognitive dysfunction, a disability strongly correlated with hearing loss.
